Health benefits

Humans need to maintain an adequate dietary intake of folate during various stages of their lives. Folate plays an essential role in cell division and DNA synthesis and is involved in periods of rapid growth and development, such as pregnancy and infancy. Folate is particularly important to help develop the baby’s skull and spinal cord, which is why low levels of this vitamin, before and during pregnancy, can lead to severe birth defects, called neural tube defects.

Folate also contributes to many other functions in the body. For example, it works together with vitamin B12 to create our genetic material (DNA), form healthy red blood cells, and support the normal functioning of our brain and nervous system. Both vitamins, alongside vitamin B6, also collaborate in the breaking down of homocysteine, an amino acid that can put us at higher risk of cardiovascular disease, when present in high amounts.

Folate deficiency has far-reaching negative health consequences at all stages of life and has been implicated in the aetiology of a variety of disorders including anaemia, various forms of cardiovascular diseases, Alzheimer’s disease and osteoporosis, all which have become pervasive health issues around the world in the 20th century.

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Quatrefolic health benefits beauty


Folate is essential for the biosynthesis of purines and thymidylate, affecting DNA replication and cell division. An active folate supplement, such as Quatrefolic®, plays an important role in mitotically active tissues. It has been shown to have skin cell-regenerating properties and supports hair vitality and nail health.
Quatrefolic health benefits sport and energy

Sport & Energy

Sports supplementation is an essential component in optimizing an athlete’s performance and overall health. B vitamins, such as active folate supplements, are vital for exercise because they are involved in the regulation of energy metabolism.

Infants and Children

Infants, children, and adolescents are in a critical phase of growth and the proper level of folate is recommended to prevent a variety of medical conditions such as anemia.


Quatrefolic® can make a difference, bypassing folate metabolism disturbances, improving fertility and increasing success rates in infertility treatment.


Quatrefolic® helps maintain sufficient levels of folate during pregnancy, lowering the risk of neural tube defects (NTDs) and birth defects.


Quatrefolic® is a safe and effective option for all women, helpful not only for hot flashes but for general women's health.


Quatrefolic® can promote healthier heart life reaching better blood levels of folate directly translates to lower homocysteine levels especially for people with MTHFR polymorphism.


By ensuring the right dosage of biologically active folate, Quatrefolic®, the salt of glucosamine 5-MTHF, allows the full enjoyment of the golden years.


Supplementation with folate may help reduce unbalanced mood symptoms. In particular, the active form 5-MTHF is needed in the brain for the synthesis of norepinephrine, serotonin, and dopamine.


People worldwide are living longer. Today most people can expect to live into their sixties and beyond. Every country in the world is experiencing growth in both the size and the proportion of older persons in the population.

Glucose Metabolism

Low folate levels are often observed in diabetes patients and result in high homocysteine levels, a recognized risk factor for cardiovascular disease and type 2 diabetes.
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