Hot flashes are the most common symptom of menopause, experienced by up to 75% of menopausal women. The symptoms last on average 5 to 10 years and can trigger further problems, including insomnia, anxiety and depression, memory and concentration issues, and lower libido.
Although hormone replacement therapy is the first treatment option for hot flashes, there are some small but still relevant associated risks, including blood clots, breast cancer, heart disease, and stroke.
Folate has been shown as a natural way to significantly reduce symptoms and is recommended as an affordable and accessible part of hot flash treatment regimens. In its active form, it is essential for the biosynthesis of the monoamine neurotransmitters, increasing mood-stabilizing serotonin activities and lowering stress-inducing noradrenaline.
Studies also show that approximately 30% of people aged 65 and over are deficient in folate – a problem only set to increase as we prepare for 22% of the world to be over 60 in 2050.
Healthy ageing researchers notes that folate – alongside vitamin B12 – is part of the essential dietary makeup needed for nerve function, brain, red blood cell and DNA health. Low folate levels are also associated with worse immunity.
Yet older people are often found to be folate deficient, a problem which has been found to increase with age. Studies have found that upwards of 23% of adults over the age of 80 are low or deficient in folate.
The active form of folate is believed to help to re-establish folate levels and counter the issues associated with low folate, with EFSA-approved health claims that active folate can improve psychological function, reduce fatigue, and have positive effects on cell division, normal homocysteine metabolism and immune system function.
By providing the natural and bioactive dose of folate directly, without the need for metabolization or enzymes like MTHFR, Quatrefolic® is immediately available for use in the body.