Folate-dependent one carbon metabolism and the role of nutritional compounds in regulating biochemical pathways in our bodies are the focus of recent and future investigative research.

Often referred to as the Methylation Cycle, this life critical process is a network of interrelated biochemical reactions that involves the transfer of one carbon methyl groups from one compound to another. Folate and Methionine are the key components of the Methylation Cycle and are required for normal healthy cellular function.

This process occurs in all cells of the body and it is crucial for a variety of functions, including detoxification, energy production, immune function, maintaining and regulating genes, mood balancing and controlling inflammation.

Therefore, maintaining the balance and levels of folate, vitamin B12 and S-Adenosyl methionine (SAMe) can be critical to support various cellular processes, which influence the development, prevention and treatment of various disease states.

Quatrefolic®, the most bioavailable form of folate, can be the preferred choice for active folate supplementation in synergy with SAMe to support and regulate the methylation cycle.

One-Carbon Metabolism

Gnosis Advanced Nutrition for One Carbon Metabolism

Gnosis is the pioneer in the development of products involved in the Methylation Cycle and one carbon metabolism network.

Methylation is involved in almost every bodily biochemical reaction, and occurs billions of times every second in our cells. That's why figuring out where the one carbon metabolism cycle can better perform its tasks contributes to health improvement, and reduce symptoms.

In recent years clinical and epidemiological evidences have helped to clarify how nutritional supplements can rectify one-carbon cycle activity, restoring normal production of key metabolites and the methylation status, and supporting the right gene expression.

Quatrefolic® and Adonat®, can be combined for a synergistic effect to support and regulate the methylation cycle.

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