Folic Acid vs. Active Folate:
Why the Difference Matters for Your Health

In recent years, increasing evidence of the advantages of reduced folate, such as Quatrefolic^®, vs folic acid has been found.

Demands for folate increase during pregnancy, but not all folates are the same. The body can’t just use folic acid, as it has to go through a conversion process into a form called Methyltetrahydrofolate (MTHF) to use it. But up to one-third of women have genetic variants that can get in the way of this specific process, and those who do may not be able to utilize folic acid as efficiently as possible.

Quatrefolic^® is the innovative form of folate. It doesn’t undergo the same conversion process as folic acid, effectively bypassing that genetic variation. 

Thanks to its high solubility, enhanced bioavailability, and other features, the glucosamine salt of 5-MethylTetraHydroFolate, Quatrefolic^®, reveals significant advantages over the previous folate generations. Quatrefolic^® delivers “finished” folate that the body can immediately use without any metabolization; it is immediately bioavailable for its biological action without being metabolized in the body.