Active Folates are Vital for Healthy Pregnancies and Post-Partum

Folate requirements increase during pregnancy. Without adequate supplementation, maternal serum folate concentrations gradually subside from the fifth month of pregnancy and remain low for several months after delivery (Smits and Essed, 2001).
One study found that the prevalence of post-partum depression was significantly higher among pregnant women taking folic acid for 6 months or less than those who reported taking folic acid for more than 6 months during pregnancy.
Quatrefolic® may offer protection against mood impairment during pregnancy and postpartum through normalizing folate levels.
In another study conducted in pregnant women, researchers observed that women homozygous for the MTHFR C677T genotype had higher levels of depressive symptoms during pregnancy.
If we assume there is a link between low folate and depression risk, this study suggests that standard folate supplementation may not adequately compensate for the folate deficiency observed in women homozygous for the C677T genotype of the MTHFR enzyme.
Choosing the right prenatal vitamins containing the active form of folate like Quatrefolic®, could provide a great advantage for women who could trust in the effective bioavailability of the 5-MTHF, independent of the presence or absence of MTHFR polymorphism.
The demand for folate increases when human cell growth is very active, notably during fetal development. Studies have found that low dietary intake of folate raises the risk of delivering a child with several types of birth defects, particularly neural tube defects and possibly leading to poor growth of the fetus or placenta.
Critical times for childbearing-aged women to consume folate is periconception and during the first trimester a time when many women are unaware they are pregnant. Therefore, it is recommended that all women of childbearing age should ensure their folate levels are substantial before, during and after pregnancy.
Quatrefolic® as a source of (6S)-5-methyltetrahydrofolate provides the nutritionally active form of folate and is supported by clinical research.