News
Active Folate Improves Blood Glucose Balance
9 May 2024
Prediabetes entails having blood glucose levels higher than the normal threshold, but lower than the level associated with a diabetes diagnosis but associated with a higher risk of developing diabetes.
Quatrefolic®, glucosamine salt of the 5-MTHF, represents a natural-based approach to help manage glycemic problems, diabetes progression, and diabetes complications.
The estimates suggest that the number of individuals affected by prediabetes is increasing rapidly in all areas of the world. A better understanding of prediabetes could help with earlier identification, thereby allowing earlier intervention, and potentially lowering the number of individuals who go on to develop diabetes.
In this context, it is important to consider the role of lifestyle intervention in achieving long-term behavioral changes in people at high risk of developing type 2 diabetes.
A recent overview of systematic reviews showed that there is sufficient evidence that lifestyle intervention, which often includes regular dietary advice and physical activity instruction, can delay or prevent the onset of type 2 diabetes in people with prediabetes.
Behind the mechanisms of T2DM and Folate
Folate deficiency contributes to elevated Homocysteine concentrations (HHcy), a recognized risk factor for cardiovascular disease and T2DM development. In T2DM development, acute and prolonged exposure to HHcy has adverse effects on the cell viability of pancreatic β-cells.
The right supplementation with active folate, such as Quatrefolic®, can ameliorate DNA methylation and improve glycemic control and endothelial function.
Globally, folate supplementation seems to significantly decrease fasting blood glucose, serum insulin, and insulin resistance.
Request your copy of the brochure “Active Folate and Glucose Metabolism” to know more.
