Quatrefolic^® News

Groundbreaking research from Amsterdam UMC, published in Nature Communications, reveals that each pregnancy leaves a distinct neurological imprint on the maternal brain. Quatrefolic^®, the biologically active folate, supports these neurological adaptations with immediate bioavailability, ensuring mothers receive the essential nutrients their changing brains need, from first conception through subsequent pregnancies.

Quatrefolic®, the leading biologically active folate (5-MTHF), in partnership with Eigenmann & Veronelli, a premier distributor of high-quality ingredients, successfully hosted an exclusive seminar on September 23 in Milan. The event brought together clients from the Italian and international markets to explore the critical role of active folate in women’s health across all life stages—from adolescence to pregnancy, menopause, and beyond.

The growing focus on active folate is reshaping the prenatal supplement landscape, with innovative formulations increasingly turning to 5-MTHF as a direct source of biologically active folate.

The World Packaging Organization (WPO) has officially established World Packaging Day, an international event to be celebrated every year on 6 September, the anniversary of the organisation’s foundation.

The dietary supplements market continues to evolve at an unprecedented pace, driven by increasingly informed consumers, emerging wellness needs, and a growing demand for innovative solutions. Today, innovation goes beyond developing new products; it means anticipating market trends, leveraging scientific research, and transforming ideas into meaningful opportunities.

A new double-blind, placebo-controlled study has found that a multivitamin with active folate, such as Quatrefolic^®, can rapidly correct widespread folate deficiency in apparently healthy adults, with no safety concerns.

Maintaining adequate folate levels during pregnancy is essential for fetal development, but new research suggests that both insufficient and excessively high maternal folate concentrations may be associated with an increased risk of congenital heart defects (CHDs) in offspring.

New research highlights the critical link between folate and B12 deficiencies and chronic fatigue. At the same time, emerging science reveals the superior benefits of bioactive folates, such as Quatrefolic^®, for energy, cognition, and metabolic health.

Polycystic Ovary Syndrome (PCOS) is one of the most common endocrine disorders affecting women of reproductive age, impacting an estimated 6–13% of women worldwide.