Quatrefolic^® News

A recent study highlighted the relationship between folate levels in maternal serum and congenital heart diseases among babies. Quatrefolic^®, the active folate, doesn't need to be metabolized, and it is readily available for the mother, supporting the proper development of the fetus.

On June 6, 2025, Gnosis by Lesaffre proudly participated as the Title Sponsor of the New Nutrition Forum in Hangzhou, an event that brought together leading minds in the health and nutrition industry. As part of the scientific program, Gnosis hosted a dedicated seminar on Quatrefolic^®, our fourth-generation folate.

Women's health is no longer just about reproductive care—it’s time we broaden the conversation.

Folate deficiency can lead to various symptoms, with fatigue being one of the most common and noticeable. This tiredness is often persistent and does not improve with rest, but it can be effectively relieved with the correct supplementation, such as Quatrefolic^®.

MethylTetraHydroFolate Reductase (MTHFR) is one of the most important enzyme in human physiology, and its deficiencies in production or function have been associated with increased risk in pregnancy and other human diseases. MTHFR polymorphism is one of the main area of current research.

The global liquid dietary supplements market continues to expand steadily, fueled by growing consumer focus on health and wellness, the convenience of liquid formats, and a rising interest in personalized nutrition solutions.

Low 5-MTHF levels can contribute to elevated homocysteine, which is linked to mood disorders. Quatrefolic^® effectively reduces homocysteine levels, crossing the Blood-Brain Barrier without needing metabolic conversion, ensuring optimal brain health and mood stability.

An interesting clinical trial brings encouraging news for women with polycystic ovary syndrome (PCOS), suggesting that folate supplementation may significantly improve key markers of inflammation and oxidative stress. Quatrefolic^®, the active form of folate, can reduce the damage caused by oxidation.

Are you curious about the powerful role of Active Folate, like Quatrefolic^®, in supporting women’s health? From pregnancy and fertility to menopause and beyond, Quatrefolic^® offers incredible benefits at every stage of life. Want to know more?