QUATREFOLIC® White Paper lets you know why it is the paramount folate for everyone

Gnosis S.p.A., proprietary of the blockbuster ingredient Quatrefolic®, is proud to announce the publication of Quatrefolic® White Paper, a new tool to know more about this key ingredient and its powerful role in human health.

The paper sets out the key considerations on folate world, awarding outcomes that demonstrate the peculiar advantages of Quatrefolic® supplementation, the glucosamine salt of theiologically active form of folate, the 5-methyltetrahydrofolate (5-MTHF), versus folic acid.

The White Paper is a vision to unlock the great potential and opportunities of this folate, explaining how and why Quatrefolic® is winning consumer preferences where it has been already introduced.

The informative report sheds light on new research topics of folate application with specific reference to:

  • The role of impaired and/or defective enzymes involved in the metabolization of folate and folic acid (low enzyme expression and/or polymorphisms)
  • The global concerns about UMFA, unmetabolized folic acid in serum, and its potential harmless effects
  • The innovation of Quatrefolic® to solves some problems about folate supplementation:
  • The limited ability of human gut to reduce folic acid to 5-MTHF and related risk that the majority of a physiologic oral dose of FA passes into the portal venous circulation in an unmodified form.
  • The big variations in how efficiently folic acid in converted to the bioactive form in different people due to defect of MTHFR activity.
  • Health connections of folate and powerful role of 5-methyltetrahydrofolate in human health

"Every day new evidence is shared by the scientific community and is designed to educate and inform health practitioners and final consumers about folate deficiency and its role in congenic and chronic disease," - said Silvia Pisoni Marketing Manager of Gnosis - "while folic acid supplementation continues to be actively debated in the medical literature, with conflicting findings regarding its significance. Without forgetting the scientific and technical aspects that distinguish Quatrefolic® from the other folates, we have chosen an intuitive and synthetic style of communication addressed to distributors/manufactures and end-users, who ever more look to their health and want to increase their awareness. The White Paper allows the reader to go into the world of folate and understand what a revolution is taking place with Quatrefolic®".

Quatrefolic® is the glucosamine salt of (6S)-5-methyltetrahydrofolate and is structurally analogous to the reduced and active form of folic acid so Quatrefolic® completely bypasses the "damaged" MTHFR conversion step and delivers a "finished" folate the body can immediately use.

Quatrefolic® White Paper is available HERE.

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