Quatrefolic^® News

A recently new published study (Mazza et al., Nutraceutical approaches to homocysteine lowering in hypertensive subjects at low cardiovascular risk: a multicenter, randomized clinical trial. J Biol Regul Homeost Agents. 2016) has investigated the efficacy of Quatrefolic^® (400 mcg of Quatrefolic^® plus B6, and B12 BID) in lowering homocysteine serum levels (HCys) versus a conventional vitamin supplementation with highly dosed folic acid (5 mg/day) in hypertensive subjects at low cardiovascular risk.

The importance of the consumption of folate to support the body's well-being is now widely recognized and folate definitely represents one of the most common nutritional ingredients used during all stages of life.

Gnosis is proud to announce that on August 9th, 2016 Quatrefolic^® (Levomefolate glucosamine or also (6S)-5-MTHF glucosamine salt), the biologically active form of the naturally-occurring predominant form of folate, has been approved as permitted ingredient for listed medicines by TGA (Therapeutic Goods Administration) a part of the Australian Government Department of Health, responsible for regulating therapeutic goods including vitamins and minerals.

Low folate concentrations have been associated with both an increased incidence of depression and an inadequate response to treatment.

A brand-new Quatrefolic^® tool is available! Now you can find a clear chart that explains the folate metabolic pathway, from folic acid to active 5-methyltetrahydrofolate (5-MTHF)! As a matter of fact, folic acid must be converted to an active form before it is used by the body.

Gnosis is proud to announce that its commitment to providing innovative solutions to global well-being and health care challenges has been rewarded at NutraIngredients Award 2016, winning in the FINISHED PRODUCT OF THE YEAR - medical food category with Xaquil™XR from Xymogen, a new finished product formulated with Quatrefolic^®.

The partnership between Gnosis and the US nutraceutical producer Xymogen is proving successful!

Gnosis is pleased to announce that on February 16th, 2016 Quatrefolic^®, the biologically active form of the naturally-occurring predominant form of folate, has been approved as food additive by the Ministry of Health of the People's Republic of China (MOH).

Newly results about association between prenatal folate status and children's brain anatomy have been showed in a research published in the British Journal of Nutrition in early 2016 (Ars et al 2016 - Prenatal folate, homocysteine and vitamin B12 levels and child brain volumes, cognitive development and psychological functioning.)