Quatrefolic®: the new Food Nutritional Fortification Substance authorized in China

DESIO, Italy – November, 9th 2017

With an official notification [2017, No. 8] issued on October 20th 2017 by the National Health and Family Planning Commission of the PRC (former Ministry of Health of the People's Republic of China), Quatrefolic® has been publicly authorized as Food Nutritional Fortification Substance with a specific monograph that describes its quality (physical, chemical and microbiological) requirements.

After the first positive assessment made by the China National Center for Food Safety Risk assessment (CFSA) on early 2016, the use of Quatrefolic® as Food Nutritional Fortification Substance now enters in force in China.

The published monograph defines dosage and intended use of Quatrefolic®, the 5-MTHF glucosamine salt, as a new active ingredient, introducing this innovative folate instead of the already known folic acid.

Quatrefolic® is the metabolically active folate that is not affected by the common impairments of folate metabolism since it does not require the complex absorption, metabolic and enzymatic steps that are required by folic acid.

Contrary to folic acid, Quatrefolic® - being the metabolically active form of folate - is not influenced by the polymorphism of the MTHFR (methyltetrahydrofolate reductase) enzyme, a genetic defect with a high incidence in Chinese population.

Here below the official publication:


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